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4ZSQ:
Bace Crystal Structure With Tricyclic Aminothiazine Inhibitor
PDB ID:
4ZSQ
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MMDB ID:
130001
PDB Deposition Date:
2015/5/13
Updated in MMDB:
2015/06
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4ZSQ: monomeric; determined by author and by software (PISA)
Molecular Components in 4ZSQ
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-[(4s,4as,6s,8ar)-10-Aminohexahydro-3h-4,8a-(Epithiomethenoazeno)isochromen-6(1h)-Yl]-3-Chlorobenzamide
2
1
Glycerol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303