4ZQO: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor Q67

PDB ID: 4ZQODownload
MMDB ID: 130185
PDB Deposition Date: 2015/5/10
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.76  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZQO: tetrameric; determined by author and by software (PISA)
Molecular Components in 4ZQO
Label Count Molecule
Proteins (4 molecules)
4
Inosine-5'-monophosphate Dehydrogenase,inosine-5'-monophosphate Dehydrogenase
(Gene symbol: guaB2)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
4
INOSINIC ACIDINOSINIC ACID
2
4
N~2~-(2,3-dichlorophenyl)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]-L-alaninamideN~2~-(2,3-dichlorophenyl)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]-L-alaninamide
3
4
POTASSIUM IONPOTASSIUM ION
4
4
GLYCEROLGLYCEROL
5
4
S-1,2-PROPANEDIOLS-1,2-PROPANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303