4ZQN: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor P41

PDB ID: 4ZQNDownload
MMDB ID: 130184
PDB Deposition Date: 2015/5/10
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZQN: tetrameric; determined by author and by software (PISA)
Molecular Components in 4ZQN
Label Count Molecule
Proteins (4 molecules)
4
Inosine-5'-monophosphate Dehydrogenase,inosine-5'-monophosphate Dehydrogenase
(Gene symbol: guaB2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
INOSINIC ACIDINOSINIC ACID
2
4
2-chloro-N,N-dimethyl-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]benzamide2-chloro-N,N-dimethyl-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303