4ZPF: Bace1 In Complex With 8-(3-((1-aminopropan-2-yl)oxy)benzyl)-4- (cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en- 2-one

PDB ID: 4ZPFDownload
MMDB ID: 131495
PDB Deposition Date: 2015/5/7
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZPF: monomeric; determined by author
Molecular Components in 4ZPF
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-(3-{[(2s)-1-Aminopropan-2-Yl]oxy}benzyl)-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-1,3,8-Triazaspiro[4.5]dec-3-En-2-One8-(3-{[(2s)-1-Aminopropan-2-Yl]oxy}benzyl)-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-1,3,8-Triazaspiro[4.5]dec-3-En-2-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303