4ZOJ: Methylsulfanyl-containing inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

PDB ID: 4ZOJDownload
MMDB ID: 139083
PDB Deposition Date: 2015/5/6
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZOJ: dimeric; determined by author and by software (PISA)
Molecular Components in 4ZOJ
Label Count Molecule
Proteins (2 molecules)
2
Anthranilate Phosphoribosyltransferase
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose
3
2
4-methyl-2-{[2-methyl-6-(methylsulfanyl)phenyl]amino}benzoic acid4-methyl-2-{[2-methyl-6-(methylsulfanyl)phenyl]amino}benzoic acid
4
1
PHOSPHATE IONPHOSPHATE ION
5
1
IMIDAZOLEIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303