4ZMG: Crystal structure of Human Dihydroorotate Dehydrogenase (DHODH) with DH03A338

PDB ID: 4ZMGDownload
MMDB ID: 138768
PDB Deposition Date: 2015/5/4
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZMG: monomeric; determined by author and by software (PISA)
Molecular Components in 4ZMG
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase (Quinone), Mitochondrial
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
2
1
OROTIC ACIDOROTIC ACID
3
1
1-(3,5-difluoro-3'-methoxybiphenyl-4-yl)-3-(1,3-thiazol-5-yl)urea1-(3,5-difluoro-3'-methoxybiphenyl-4-yl)-3-(1,3-thiazol-5-yl)urea
4
2
SULFATE IONSULFATE ION
5
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303