4ZLZ: Crystal Structure of Bruton's Tyrosine Kinase in complex with a substituted Cinnoline

PDB ID: 4ZLZDownload
MMDB ID: 130594
PDB Deposition Date: 2015/5/1
Updated in MMDB: 2015/08
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZLZ: monomeric; determined by author and by software (PISA)
Molecular Components in 4ZLZ
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase BTK
(Gene symbol: BTK)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
IMIDAZOLEIMIDAZOLE
2
1
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303