4ZLO: Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1

PDB ID: 4ZLODownload
MMDB ID: 131493
PDB Deposition Date: 2015/5/1
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZLO: dimeric; determined by author and by software (PISA)
Molecular Components in 4ZLO
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase PAK 1
(Gene symbol: PAK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303