4ZK4: Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane

PDB ID: 4ZK4Download
MMDB ID: 129308
PDB Deposition Date: 2015/4/29
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 1.901  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZK4: pentameric; determined by author and by software (PISA)
Molecular Components in 4ZK4
Label Count Molecule
Proteins (5 molecules)
5
Soluble Acetylcholine Receptor, Neuronal Acetylcholine Receptor Subunit Alpha-3 Chimera
(Gene symbol: CHRNA3)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
5
SULFATE IONSULFATE ION
3
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
4
2
(5R)-1-methyl-7-[5-(propan-2-yloxy)pyridin-3-yl]-1,7-diazaspiro[4.4]nonane(5R)-1-methyl-7-[5-(propan-2-yloxy)pyridin-3-yl]-1,7-diazaspiro[4.4]nonane
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303