4ZFI: Structure of Mdm2 with low molecular weight inhibitor

PDB ID: 4ZFIDownload
MMDB ID: 144056
PDB Deposition Date: 2015/4/21
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZFI: monomeric; determined by author
Molecular Components in 4ZFI
Label Count Molecule
Protein (1 molecule)
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol: MDM2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5S)-3,5-bis(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-hydroxy-1-methyl-1,5-dihydro-2H-pyrrol-2-one(5S)-3,5-bis(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-hydroxy-1-methyl-1,5-dihydro-2H-pyrrol-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303