4ZAE: Development of a novel class of potent and selective FIXa inhibitors

PDB ID: 4ZAEDownload
MMDB ID: 129804
PDB Deposition Date: 2015/4/13
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.86  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZAE: dimeric; determined by author and by software (PISA)
Molecular Components in 4ZAE
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor IX
(Gene symbol: F9)
Molecule annotation
1
Coagulation Factor IX
(Gene symbol: F9)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2,6-dichloro-N-[(2R)-2-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-phenylethyl]-4-(4H-1,2,4-triazol-4-yl)benzamide2,6-dichloro-N-[(2R)-2-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-phenylethyl]-4-(4H-1,2,4-triazol-4-yl)benzamide
2
1
SODIUM IONSODIUM ION
3
1
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303