4Z93: BRD4 bromodomain 2 in complex with gamma-carboline-containing compound, number 18

PDB ID: 4Z93Download
MMDB ID: 130575
PDB Deposition Date: 2015/4/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.27  Å
Source Organism:
Similar Structures:
Biological Unit for 4Z93: monomeric; determined by author and by software (PISA)
Molecular Components in 4Z93
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-5H-pyrido[4,3-b]indole1-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-5H-pyrido[4,3-b]indole
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303