4Z77: Weak TCR binding to an unstable insulin epitope drives type 1 diabetes

PDB ID: 4Z77Download
MMDB ID: 130360
PDB Deposition Date: 2015/4/6
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 4Z77: trimeric; determined by author and by software (PISA)
Molecular Components in 4Z77
Label Count Molecule
Proteins (3 molecules)
1
H-2 Class I Histocompatibility Antigen, K-D Alpha Chain
Molecule annotation
1
Beta-2-microglobulin
Molecule annotation
1
Insulin
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
5
GLYCEROLGLYCEROL
2
1
POLYETHYLENE GLYCOL (N=34)POLYETHYLENE GLYCOL (N=34)
3
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303