4Z46: X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin

PDB ID: 4Z46Download
MMDB ID: 129632
PDB Deposition Date: 2015/4/1
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 4Z46: monomeric; determined by software (PISA)
Molecular Components in 4Z46
Label Count Molecule
Protein (1 molecule)
1
Lysozyme C
(Gene symbol: LYZ)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
9
NITRATE IONNITRATE ION
3
2
SODIUM IONSODIUM ION
4
1
CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)
5
1
CisplatinCisplatin
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303