4Z3O: Quinolone(Moxifloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae

PDB ID: 4Z3ODownload
MMDB ID: 142953
PDB Deposition Date: 2015/3/31
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 3.44  Å
Source Organism:
Streptococcus pneumoniae▼
Similar Structures:
Biological Unit for 4Z3O: hexameric; determined by software (PISA)
Molecular Components in 4Z3O
Label Count Molecule
Proteins (2 molecules)
2
DNA Topoisomerase 4 Subunit B,pare30-parc55 Fused Topo IV From S. Pneumoniae
Molecule annotation
Nucleotides(4 molecules)
1
E-site DNA
Molecule annotation
1
E-site DNA
Molecule annotation
1
E-site DNA
Molecule annotation
1
E-site DNA
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303