4Z2B: The structure of human PDE12 residues 161-609 in complex with GSK3036342A

PDB ID: 4Z2BDownload
MMDB ID: 130150
PDB Deposition Date: 2015/3/29
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4Z2B: monomeric; determined by author and by software (PISA)
Molecular Components in 4Z2B
Label Count Molecule
Protein (1 molecule)
1
2',5'-phosphodiesterase 12
(Gene symbol: PDE12)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
SULFATE IONSULFATE ION
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
4
1
3-(6-{[(2S,3S)-3-(hydroxymethyl)-2-phenylmorpholin-4-yl]carbonyl}-1-methyl-1H-benzimidazol-2-yl)-1H-indole-6-carbonitrile3-(6-{[(2S,3S)-3-(hydroxymethyl)-2-phenylmorpholin-4-yl]carbonyl}-1-methyl-1H-benzimidazol-2-yl)-1H-indole-6-carbonitrile
5
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303