4Z1S: Crystal Structure Of The First Bromodomain Of Human Brd4 With Benzotriazolo-diazepine Scaffold

PDB ID: 4Z1SDownload
MMDB ID: 128509
PDB Deposition Date: 2015/3/27
Updated in MMDB: 2016/04
Experimental Method:
x-ray diffraction
Resolution: 1.06  Å
Source Organism:
Similar Structures:
Biological Unit for 4Z1S: monomeric; determined by author and by software (PISA)
Molecular Components in 4Z1S
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[(4s)-6-(4-Chlorophenyl)-1,4-Dimethyl-5,6-Dihydro-4h-[1,2,4]triazolo[4,3-A][1,5]benzodiazepin-8-Yl]pyridin-2-Amine5-[(4s)-6-(4-Chlorophenyl)-1,4-Dimethyl-5,6-Dihydro-4h-[1,2,4]triazolo[4,3-A][1,5]benzodiazepin-8-Yl]pyridin-2-Amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303