4Z0Q: Carbonic anhydrase inhibitors: Design and synthesis of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hCA VII, hCA IX, and hCA XIV)

PDB ID: 4Z0QDownload
MMDB ID: 132043
PDB Deposition Date: 2015/3/26
Updated in MMDB: 2015/08
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 4Z0Q: monomeric; determined by software (PISA)
Molecular Components in 4Z0Q
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
4-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)benzenesulfonamide4-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303