4YZ9: Crystal Structure of human phosphorylated IRE1alpha in complex with a type III kinase inhibitor (GSK2850163A)

PDB ID: 4YZ9Download
MMDB ID: 134044
PDB Deposition Date: 2015/3/24
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.463  Å
Source Organism:
Similar Structures:
Biological Unit for 4YZ9: monomeric; determined by author
Molecular Components in 4YZ9
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase/endoribonuclease Ire1
(Gene symbol: ERN1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5R)-2-(3,4-dichlorobenzyl)-N-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide(5R)-2-(3,4-dichlorobenzyl)-N-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303