4YVC: ROCK 1 bound to thiazole inhibitor

PDB ID: 4YVCDownload
MMDB ID: 129978
PDB Deposition Date: 2015/3/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4YVC: dimeric; determined by author and by software (PISA)
Molecular Components in 4YVC
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase 1
(Gene symbol: ROCK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-fluoro-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide2-fluoro-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303