4YU2: Crystal structure of DYRK1A with harmine-derivatized AnnH-75 inhibitor

PDB ID: 4YU2Download
MMDB ID: 128159
PDB Deposition Date: 2015/3/18
Updated in MMDB: 2015/03
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4YU2: monomeric; determined by author
Molecular Components in 4YU2
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
2
1
(1-chloro-7-methoxy-9H-beta-carbolin-9-yl)acetonitrile(1-chloro-7-methoxy-9H-beta-carbolin-9-yl)acetonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303