4YT7: Factor VIIa in complex with the inhibitor 2-(2-{(R)-[(4-carbamimidoylphenyl)amino][5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl]methyl}-1H-imidazol-4-yl)benzamide

PDB ID: 4YT7Download
MMDB ID: 128934
PDB Deposition Date: 2015/3/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4YT7: dimeric; determined by author and by software (PISA)
Molecular Components in 4YT7
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor VII (Heavy Chain)
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII (Light Chain)
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
2-[2-[(R)-[(4-carbamimidoylphenyl)amino]-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)methyl]-1H-imidazol-4-yl]benzamide2-[2-[(R)-[(4-carbamimidoylphenyl)amino]-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)methyl]-1H-imidazol-4-yl]benzamide
2
1
CALCIUM IONCALCIUM ION
3
4
SULFATE IONSULFATE ION
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303