4YLL: Crystal structure of DYRK1AA in complex with 10-Bromo-substituted 11H-indolo[3,2-c]quinolone-6-carboxylic acid inhibitor 5t

PDB ID: 4YLLDownload
MMDB ID: 128152
PDB Deposition Date: 2015/3/5
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 4YLL: monomeric; determined by author
Molecular Components in 4YLL
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
5
SULFATE IONSULFATE ION
2
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
10-bromo-2-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid10-bromo-2-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303