4YL1: Crystal Structures of mPGES-1 Inhibitor Complexes

PDB ID: 4YL1Download
MMDB ID: 129974
PDB Deposition Date: 2015/3/4
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.41  Å
Source Organism:
Similar Structures:
Biological Unit for 4YL1: trimeric; determined by author and by software (PISA)
Molecular Components in 4YL1
Label Count Molecule
Proteins (3 molecules)
3
Prostaglandin E Synthase
(Gene symbol: PTGES)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
3
5-(4-tert-butylphenyl)-1-[4-(propan-2-yloxy)phenyl]-1H-indole-2-carboxylic acid5-(4-tert-butylphenyl)-1-[4-(propan-2-yloxy)phenyl]-1H-indole-2-carboxylic acid
2
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
3
GLUTATHIONEGLUTATHIONE
4
6
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
5
3
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303