4YKN: Pi3K alpha lipid kinase with Active Site Inhibitor

PDB ID: 4YKNDownload
MMDB ID: 130143
PDB Deposition Date: 2015/3/4
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4YKN: monomeric; determined by author and by software (PISA)
Molecular Components in 4YKN
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 3-kinase Regulatory Subunit Alpha,phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Alpha Isoform Fusion Protein
(Gene symbol: PIK3R1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303