4YJ3: Crystal structure of tubulin bound to compound 2

PDB ID: 4YJ3Download
MMDB ID: 129617
PDB Deposition Date: 2015/3/3
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.75  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 4YJ3: hexameric; determined by author and by software (PISA)
Molecular Components in 4YJ3
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Tubulin-tyrosine Ligase
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
3
CALCIUM IONCALCIUM ION
4
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
5
2
6-(4-ethoxyphenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine6-(4-ethoxyphenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
6
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
7
1
IMIDAZOLEIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303