4Y93: Crystal structure of the PH-TH-kinase construct of Bruton's tyrosine kinase (Btk)

PDB ID: 4Y93Download
MMDB ID: 127965
PDB Deposition Date: 2015/2/16
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.695  Å
Source Organism:
Similar Structures:
Biological Unit for 4Y93: monomeric; determined by author and by software (PISA)
Molecular Components in 4Y93
Label Count Molecule
Protein (1 molecule)
1
Non-specific Protein-tyrosine Kinase,non-specific Protein-tyrosine Kinase
(Gene symbol: BTK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide
3
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303