4Y5D: Crystal Structure Of Alis2-streptavidin Complex

Citation:
Abstract
Artificial ligands of streptavidin (ALiS) with association constants of approximately 10(6) M(-1) were discovered by high-throughput screening of our chemical library, and their binding characteristics, including X-ray crystal structure of the streptavidin complex, were determined. Unlike biotin and its derivatives, ALiS exhibits fast dissociation kinetics and excellent cell permeability. The streptavidin-ALiS system provides a novel, practical compound-dependent methodology for repeated reversible cycling of protein localization between intracellular organella.
PDB ID: 4Y5DDownload
MMDB ID: 132834
PDB Deposition Date: 2015/2/11
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4Y5D: tetrameric; determined by author and by software (PISA)
Molecular Components in 4Y5D
Label Count Molecule
Proteins (4 molecules)
4
Streptavidin
Molecule annotation
Chemicals (7 molecules)
1
3
2
1
3
1
4
2
* Click molecule labels to explore molecular sequence information.

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