4Y14: Structure of protein tyrosine phosphatase 1B complexed with inhibitor (PTP1B:CPT157633)

PDB ID: 4Y14Download
MMDB ID: 131450
PDB Deposition Date: 2015/2/6
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.898  Å
Source Organism:
Similar Structures:
Biological Unit for 4Y14: monomeric; determined by author and by software (PISA)
Molecular Components in 4Y14
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
CHLORIDE IONCHLORIDE ION
2
3
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
3
1
GLYCEROLGLYCEROL
4
1
3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-Nalpha-(methylsulfonyl)-L-phenylalaninamide3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-Nalpha-(methylsulfonyl)-L-phenylalaninamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303