4XY9: Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine ligand

PDB ID: 4XY9Download
MMDB ID: 127771
PDB Deposition Date: 2015/2/2
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 4XY9: monomeric; determined by author and by software (PISA)
Molecular Components in 4XY9
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303