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Biotechnology Information

4XXR: Atomic Resolution X-Ray Crystal Structure of a Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with CTX-M-14 E166A Beta-Lactamase

PDB ID:	4XXR Download
MMDB ID:	127955
PDB Deposition Date:	2015/1/30
Updated in MMDB:	2019/12
Experimental Method:	x-ray diffraction
Resolution:	1.18 Å
Source Organism:	Escherichia coli
Similar Structures:

Biological Unit for 4XXR: monomeric; determined by author

Molecular Components in 4XXR
Label	Count	Molecule
Protein (1 molecule)
A	1	Ctx-m-14 Class a Beta-lactamase (Gene symbol: blaCTX-M-14)
Chemicals and Non-standard biopolymers (5 molecules)
1	1	POTASSIUM ION (Link to PubChem not yet available)
2	1	[(1,2,3,4,5-eta)-1-(4-{[(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl)cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium (Link to PubChem not yet available)
3	2	[(1,2,3,4,5-eta)-1-(4-{[carboxy(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl)cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium (Link to PubChem not yet available)
4	1	[(1,2,3,4,5-eta)-1-(4-{[carboxy(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl)cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium (Link to PubChem not yet available)

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303