4XT8: Crystal structure of Rv2671 from Mycobacterium tuberculosis in complex with NADP+ and trimetrexate

PDB ID: 4XT8Download
MMDB ID: 136672
PDB Deposition Date: 2015/1/23
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 4XT8: dimeric; determined by author and by software (PISA)
Molecular Components in 4XT8
Label Count Molecule
Proteins (2 molecules)
2
Rv2671
(Gene symbol: ribD)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
TRIMETREXATETRIMETREXATE
3
4
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
2
GLYCEROLGLYCEROL
5
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303