4XO7: Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one

PDB ID: 4XO7Download
MMDB ID: 136507
PDB Deposition Date: 2015/1/16
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 4XO7: dimeric; determined by author and by software (PISA)
Molecular Components in 4XO7
Label Count Molecule
Proteins (2 molecules)
2
Aldo-keto Reductase Family 1 Member C2
(Gene symbol: AKR1C2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
4-ANDROSTENE-3-17-DIONE4-ANDROSTENE-3-17-DIONE
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303