4XJL: Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a HTS lead compound

PDB ID: 4XJLDownload
MMDB ID: 135649
PDB Deposition Date: 2015
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 4XJL: dimeric; determined by author and by software (PISA)
Molecular Components in 4XJL
Label Count Molecule
Proteins (2 molecules)
2
Adenosylmethionine-8-amino-7-oxononanoate Aminotransferase
(Gene symbol: bioA)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
2
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
3
2
N-(1,2,3-benzothiadiazol-5-yl)-4-phenylpiperazine-1-carboxamideN-(1,2,3-benzothiadiazol-5-yl)-4-phenylpiperazine-1-carboxamide
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303