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4XIR:
Discovery of novel oxazepine and diazepine carboxamides as two new classes of heat shock protein 90 inhibitors
PDB ID:
4XIR
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MMDB ID:
127539
PDB Deposition Date:
2015/1/7
Updated in MMDB:
2016/06
Experimental Method:
x-ray diffraction
Resolution:
1.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4XIR: monomeric; determined by author and by software
Molecular Components in 4XIR
Label
Count
Molecule
Protein (1 molecule)
A
1
Heat Shock Protein HSP 90-alpha
(Gene symbol:
HSP90AA1
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(6S)-2-chloro-8,11,11-trimethyl-9-oxo-6-propyl-6,7,9,10,11,12-hexahydroindolo[2,1-d][1,5]benzoxazepine-3-carboxamide
2
1
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303