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4XIR:
Discovery Of Novel Oxazepine And Diazepine Carboxamides As Two New Classes Of Heat Shock Protein 90 Inhibitors
PDB ID:
4XIR
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MMDB ID:
127539
PDB Deposition Date:
2015/1/7
Updated in MMDB:
2016/06
Experimental Method:
x-ray diffraction
Resolution:
1.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4XIR: monomeric; determined by author and by software (PISA)
Molecular Components in 4XIR
Label
Count
Molecule
Protein (1 molecule)
A
1
Heat Shock Protein HSP 90-alpha
(Gene symbol:
HSP90AA1
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(6s)-2-Chloro-8,11,11-Trimethyl-9-Oxo-6-Propyl-6,7,9,10,11,12-Hexahydroindolo[2,1-D][1,5]benzoxazepine-3-Carboxamide
2
1
Glycerol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303