4XEW: Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a HTS lead compound

PDB ID: 4XEWDownload
MMDB ID: 130706
PDB Deposition Date: 2014/12/25
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.47  Å
Source Organism:
Similar Structures:
Biological Unit for 4XEW: dimeric; determined by author and by software (PISA)
Molecular Components in 4XEW
Label Count Molecule
Proteins (2 molecules)
2
Adenosylmethionine-8-amino-7-oxononanoate Aminotransferase
(Gene symbol: bioA)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
2
6-(2-fluorophenyl)[1,3]dioxolo[4,5-g]quinolin-8(5H)-one6-(2-fluorophenyl)[1,3]dioxolo[4,5-g]quinolin-8(5H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303