4X91: Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP)

PDB ID: 4X91Download
MMDB ID: 186257
PDB Deposition Date: 2014/12/11
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4X91: monomeric; determined by author and by software (PISA)
Molecular Components in 4X91
Label Count Molecule
Protein (1 molecule)
1
Group XV Phospholipase A2
(Gene symbol: PLA2G15)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
propan-2-yl (R)-dodec-11-en-1-ylphosphonofluoridatepropan-2-yl (R)-dodec-11-en-1-ylphosphonofluoridate
3
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
4
4
PHOSPHATE IONPHOSPHATE ION
5
2
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303