4X7J: Co-crystal Structure Of Perk With 2-amino-n-[4-methoxy-3- (trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6- Yl]benzamide Inhibitor

PDB ID: 4X7JDownload
MMDB ID: 126537
PDB Deposition Date: 2014/12/9
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4X7J: monomeric; determined by author and by software (PISA)
Molecular Components in 4X7J
Label Count Molecule
Protein (1 molecule)
1
Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, Eukaryotic Translation Initiation Factor 2-alpha Kinase 3
(Gene symbol: EIF2AK3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)phenyl]-4-Methyl-3-[2-(Methylamino)quinazolin-6-Yl]benzamide2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)phenyl]-4-Methyl-3-[2-(Methylamino)quinazolin-6-Yl]benzamide
2
1
L(+)-Tartaric AcidL(+)-Tartaric Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303