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4X67: Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions

PDB ID:

MMDB ID:

126764

PDB Deposition Date:

2014/12/7

Updated in MMDB:

2024/10

Experimental Method:

x-ray diffraction

Resolution:

4.1 Å

Source Organism:

Saccharomyces cerevisiae S288C▼

Taxonomy	Molecule
Saccharomyces cerevisiae S288C	A, B, C, E, F, H, I, J, K, L
synthetic construct	R, T

Similar Structures:

Biological Unit for 4X67: dodecameric; determined by author and by software (PISA)

Molecular Components in 4X67
Label	Count	Molecule
Proteins (10 molecules)
A	1	DNA-directed RNA Polymerase II Subunit Rpb1
B	1	DNA-directed RNA Polymerase II Subunit Rpb2
C	1	DNA-directed RNA Polymerase II Subunit Rpb3
E	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc1
F	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc2
H	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc3
I	1	DNA-directed RNA Polymerase II Subunit Rpb9
J	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc5
K	1	DNA-directed RNA Polymerase II Subunit Rpb11
L	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc4
Nucleotides(2 molecules)
R	1	RNA_9 MER
T	1	Template DNA _29 MER
Chemicals and Non-standard biopolymers (8 molecules)
1	8	ZINC ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB