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4X5Z:
menin in complex with MI-136
PDB ID:
4X5Z
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MMDB ID:
128652
PDB Deposition Date:
2014/12/6
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
1.86 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4X5Z: monomeric; determined by author and by software (PISA)
Molecular Components in 4X5Z
Label
Count
Molecule
Protein (1 molecule)
A
1
Menin
(Gene symbol:
MEN1
)
Chemicals and Non-standard biopolymers (9 molecules)
1
4
SULFATE ION
2
1
5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile
3
1
TETRAETHYLENE GLYCOL
4
2
DIMETHYL SULFOXIDE
5
1
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303