4X4M: Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding

PDB ID: 4X4MDownload
MMDB ID: 128469
PDB Deposition Date: 2014/12/3
Updated in MMDB: 2018/07
Experimental Method:
x-ray diffraction
Resolution: 3.485  Å
Source Organism:
Similar Structures:
Biological Unit for 4X4M: trimeric; determined by author
Molecular Components in 4X4M
Label Count Molecule
Proteins (3 molecules)
2
IG Gamma-1 Chain C Region
(Gene symbol: IGHG1)
Molecule annotation
1
High Affinity Immunoglobulin Gamma FC Receptor I
(Gene symbol: FCGR1A)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
6
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
2
2
BETA-D-MANNOSEBETA-D-MANNOSE
3
3
ALPHA-D-MANNOSEALPHA-D-MANNOSE
4
2
BETA-L-FUCOSEBETA-L-FUCOSE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303