4X3J: Selection Of Fragments For Kinase Inhibitor Design: Decoration Is Key

PDB ID: 4X3JDownload
MMDB ID: 126386
PDB Deposition Date: 2014/11/30
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4X3J: monomeric; determined by author and by software (PISA)
Molecular Components in 4X3J
Label Count Molecule
Protein (1 molecule)
1
Angiopoietin-1 Receptor
(Gene symbol: TEK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-[4-(4-Amino-5-Oxopyrido[2,3-D]pyrimidin-8(5h)-Yl)phenyl]-3-[2-Fluoro-5-(Trifluoromethyl)phenyl]urea1-[4-(4-Amino-5-Oxopyrido[2,3-D]pyrimidin-8(5h)-Yl)phenyl]-3-[2-Fluoro-5-(Trifluoromethyl)phenyl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303