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4X2U:
X-ray crystal structure of the orally available aminopeptidase inhibitor, Tosedostat, bound to the M1 Alanyl Aminopeptidase from P. falciparum
PDB ID:
4X2U
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MMDB ID:
127191
PDB Deposition Date:
2014/11/27
Updated in MMDB:
2017/10
Experimental Method:
x-ray diffraction
Resolution:
1.5 Å
Source Organism:
Plasmodium falciparum FcB1/Columbia
Similar Structures:
VAST+
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Biological Unit for 4X2U: monomeric; determined by author
Molecular Components in 4X2U
Label
Count
Molecule
Protein (1 molecule)
A
1
M1 Family Aminopeptidase
Chemicals and Non-standard biopolymers (14 molecules)
1
1
ZINC ION
2
1
(2S)-({(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}amino)(phenyl)ethanoic acid
3
4
MAGNESIUM ION
4
8
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303