4X2U: X-ray Crystal Structure Of The Orally Available Aminopeptidase Inhibitor, Tosedostat, Bound To The M1 Alanyl Aminopeptidase From P. Falciparum

PDB ID: 4X2UDownload
MMDB ID: 127191
PDB Deposition Date: 2014/11/27
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4X2U: monomeric; determined by author
Molecular Components in 4X2U
Label Count Molecule
Protein (1 molecule)
1
M1 Family Aminopeptidase
Molecule annotation
Chemicals (14 molecules)
1
1
Zinc IonZinc Ion
2
1
(2s)-({(2r)-2-[(1s)-1-Hydroxy-2-(Hydroxyamino)-2-Oxoethyl]-4-Methylpentanoyl}amino)(Phenyl)ethanoic Acid(2s)-({(2r)-2-[(1s)-1-Hydroxy-2-(Hydroxyamino)-2-Oxoethyl]-4-Methylpentanoyl}amino)(Phenyl)ethanoic Acid
3
4
Magnesium IonMagnesium Ion
4
8
GlycerolGlycerol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes.Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303
.