4WYE: Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a DSF fragment hit

PDB ID: 4WYEDownload
MMDB ID: 130703
PDB Deposition Date: 2014/11/17
Updated in MMDB: 2015/07
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 4WYE: dimeric; determined by author and by software (PISA)
Molecular Components in 4WYE
Label Count Molecule
Proteins (2 molecules)
2
Adenosylmethionine-8-amino-7-oxononanoate Aminotransferase
(Gene symbol: bioA)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
2
phenyl(piperidin-4-yl)methanonephenyl(piperidin-4-yl)methanone
3
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
4
1
SULFATE IONSULFATE ION
5
1
ACETONEACETONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303