4WYC: Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a thiazole benzamide inhibitor

PDB ID: 4WYCDownload
MMDB ID: 130702
PDB Deposition Date: 2014/11/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4WYC: dimeric; determined by author and by software (PISA)
Molecular Components in 4WYC
Label Count Molecule
Proteins (2 molecules)
2
Adenosylmethionine-8-amino-7-oxononanoate Aminotransferase
(Gene symbol: bioA)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
2
4-(1H-imidazol-1-yl)benzamide4-(1H-imidazol-1-yl)benzamide
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
FORMYL GROUPFORMYL GROUP
5
1
SULFATE IONSULFATE ION
6
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303