4WTL: Crystal Structure Of Hcv Ns5b Genotype 2a Jfh-1 Isolate With S15g E86q E87q C223h V321i Mutations In Complex With Rna Template 5'-uacc, Rna Primer 5'-pgg, Mn2+, And Udp

PDB ID: 4WTLDownload
MMDB ID: 126959
PDB Deposition Date: 2014/10/30
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Hepatitis C virus JFH-1▼
Similar Structures:
Biological Unit for 4WTL: trimeric; determined by author
Molecular Components in 4WTL
Label Count Molecule
Protein (1 molecule)
1
RNA-directed RNA Polymerase
Molecule annotation
Nucleotides(2 molecules)
1
RNA Template Uacc
Molecule annotation
1
RNA Primer GG
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
Manganese (Ii) IonManganese (Ii) Ion
2
1
Chloride IonChloride Ion
3
1
Uridine-5'-DiphosphateUridine-5'-Diphosphate
4
1
1-(2-Methoxy-Ethoxy)-2-{2-[2-(2-Methoxy-Ethoxy]-Ethoxy}-Ethane1-(2-Methoxy-Ethoxy)-2-{2-[2-(2-Methoxy-Ethoxy]-Ethoxy}-Ethane
5
1
2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303