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4WHZ:
Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives
PDB ID:
4WHZ
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MMDB ID:
125131
PDB Deposition Date:
2014/9/24
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
1.79 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4WHZ: monomeric; determined by author and by software (PISA)
Molecular Components in 4WHZ
Label
Count
Molecule
Protein (1 molecule)
A
1
Mitogen-activated Protein Kinase 10
(Gene symbol:
MAPK10
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-{1-[(3S)-pyrrolidin-3-yl]-1H-pyrazol-4-yl}benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303