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4WE1:
Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ600)
PDB ID:
4WE1
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MMDB ID:
125294
PDB Deposition Date:
2014/9/9
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
2.491 Å
Source Organism:
Human immunodeficiency virus type 1 BH10
Similar Structures:
VAST+
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Biological Unit for 4WE1: dimeric; determined by author and by software (PISA)
Molecular Components in 4WE1
Label
Count
Molecule
Proteins (2 molecules)
A
1
Gag-pol Polyprotein
B
1
Gag-pol Polyprotein
Chemicals and Non-standard biopolymers (7 molecules)
1
1
5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}naphthalene-2-carbonitrile
2
2
MAGNESIUM ION
3
4
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303