4WE1: Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ600)

PDB ID: 4WE1Download
MMDB ID: 125294
PDB Deposition Date: 2014/9/9
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.491  Å
Source Organism:
Similar Structures:
Biological Unit for 4WE1: dimeric; determined by author and by software (PISA)
Molecular Components in 4WE1
Label Count Molecule
Proteins (2 molecules)
1
Gag-pol Polyprotein
Molecule annotation
1
Gag-pol Polyprotein
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}naphthalene-2-carbonitrile5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}naphthalene-2-carbonitrile
2
2
MAGNESIUM IONMAGNESIUM ION
3
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303