4W8D: Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06454589)

PDB ID: 4W8DDownload
MMDB ID: 127914
PDB Deposition Date: 2014/8/24
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.77  Å
Source Organism:
Similar Structures:
Biological Unit for 4W8D: monomeric; determined by author and by software (PISA)
Molecular Components in 4W8D
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 24 36 KDA Subunit
(Gene symbol: STK24)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303