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4W5Q:
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8
PDB ID:
4W5Q
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MMDB ID:
124744
PDB Deposition Date:
2014/8/18
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
3.101 Å
Source Organism:
synthetic construct
▼
Taxonomy
Molecule
synthetic construct
B, D
Homo sapiens
A
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4W5Q: trimeric; determined by author and by software (PISA)
Molecular Components in 4W5Q
Label
Count
Molecule
Protein (1 molecule)
A
1
Protein Argonaute-2
Nucleotides(2 molecules)
B
1
RNA (5'-r(p*up*up*cp*ap*cp*ap*up*up*gp*cp*cp*cp*ap*ap*gp*up*cp*u)-3')
D
1
RNA (5'-r(*ap*ap*ap*up*gp*up*gp*ap*ap*a)-3')
Chemicals and Non-standard biopolymers (7 molecules)
1
3
MAGNESIUM ION
2
4
PHENOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303